Fig. 1 · Structure
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MSU38225
Nrf-2 Inhibitor
MSU38225 is an Nrf-2 inhibitor that elevates levels of reactive oxygen species (ROS). It demonstrates significant antitumor activity by inhibiting the growth of human lung cancer cells and increasing their sensitivity to chemotherapy, both in vitro and in vivo. This compound is useful for exploring mechanisms of cancer resistance and potential therapeutic strategies in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1629160-83-3 |
| Applications | Nrf-2 Inhibitor |
| Formula | C21H19N3 |
| Molecular Weight | 313.40 |
| SMILES | N#CC1=C(NC2=CC(C)=CC(C)=C2)N=C(C)C(C3=CC=CC=C3)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.