Fig. 1 · Structure
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MTDH-SND1 blocker 2
MTDH-SND1 Blocker
MTDH-SND1 Blocker 2 (compound C19) is a potent inhibitor targeting the MTDH-SND1 complex, with an IC50 of 487 nM. It exhibits a strong binding affinity for the SND1 protein, characterized by a Kd value of 279 nM. This compound promotes SND1 protein degradation, demonstrating significant antiproliferative activity and the induction of apoptosis. MTDH-SND1 Blocker 2 is an important tool for investigating breast cancer pathways and associated therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3052204-80-2 |
| Applications | MTDH-SND1 Blocker |
| Formula | C18H12FN3O2S |
| Molecular Weight | 353.37 |
| SMILES | FC1=CC(C=CC=N2)=C2C(NS(C3=C(N=CC=C4)C4=CC=C3)(=O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.