Fig. 1 · Structure
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MTIC
Temozolomide Metabolite
MTIC, the active metabolite of Temozolomide (TMZ), functions primarily as a DNA alkylating agent. It exhibits significant antitumor activity through the formation of DNA lesions, which disrupts the integrity of the genetic material within cancer cells. This reagent is widely used in research settings to study the mechanisms of action of chemotherapy and to explore therapeutic strategies for glioblastoma and other malignant tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3413-72-7 |
| Applications | Temozolomide Metabolite |
| Formula | C5H8N6O |
| Molecular Weight | 168.16 |
| SMILES | O=C(C1=C(/N=N/NC)N=CN1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.