mTOR inhibitor-24

Catalog No.: A79762
mTOR Inhibitor
mTOR inhibitor-24 (compound 9d) is a potent mTOR inhibitor, exhibiting an IC50 of 0.34 nM against mTOR and 324 nM against PI3K-α. This compound effectively inhibits the proliferation of LNCaP cells with an IC50 of 180 nM. It serves as a valuable tool for research in cancer biology and therapeutic exploration targeting the mTOR signaling pathway.
Grouped product items
Size Price Stock Qty
1mg
$120.00
In stock
5mg
$285.00
In stock
10mg
$400.00
In stock
25mg
$560.00
In stock
50mg
$725.00
In stock
100mg
$975.00
In stock
200mg
$1,270.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionmTOR inhibitor-24 (compound 9d) is a potent mTOR inhibitor, exhibiting an IC50 of 0.34 nM against mTOR and 324 nM against PI3K-α. This compound effectively inhibits the proliferation of LNCaP cells with an IC50 of 180 nM. It serves as a valuable tool for research in cancer biology and therapeutic exploration targeting the mTOR signaling pathway.
Product Information
Catalog NumA79762
FormulaC21H23N5O3S
Molecular Weight425.50
CAS Number1144075-38-6
SMILESO=C(NCCO)NC1=CC=C(C2=NC3=C(C(N4CC5OC(CC5)C4)=N2)SC=C3)C=C1
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