Signaling Pathway
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| Discription | MTX-211 is a dual inhibitor of EGFR and PI3K, which plays important roles in the progression of KRAS mutant colorectal cancer. MTX-211 has the potential for the treatment of KRAS mutant colorectal cancer. | ||
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| Catalog Num | A18324 |
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| Formula | C20H14Cl2FN5O2S |
| Molecular Weight | 478.3234 |
| CAS Number | 1952236-05-3 |
| SMILES | CS(=O)(NC1=CC(C2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2)=CN=C1Cl)=O |
| Synonyms | MTX211, MTX 211 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 22 mg/mL (45.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.91 mL | 104.53 mL | 209.06 mL |
| 0.5 mM | 4.18 mL | 20.91 mL | 41.81 mL |
| 1 mM | 2.09 mL | 10.45 mL | 20.91 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
