Fig. 1 · Structure
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Mulberrin
OATP2B1 Inhibitor
Mulberrin is a potent inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1), exhibiting an IC50 value of 1.8 ± 1.5 μM for the uptake of estrone-3-sulfate (E3S). This compound can be utilized in research focused on drug transport mechanisms, pharmacokinetics, and the modulation of steroid hormone uptake. Its ability to regulate OATP2B1 activity makes it a valuable tool for studying potential interactions and effects of therapeutic agents on this transport pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 62949-79-5 |
| Applications | OATP2B1 Inhibitor |
| Formula | C25H26O6 |
| Molecular Weight | 422.47 |
| Synonyms | Kuwanon C |
| SMILES | C/C(C)=C\CC1=C2C(C(C(C/C=C(C)\C)=C(C3=C(C=C(O)C=C3)O)O2)=O)=C(O)C=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.