Fig. 1 · Structure
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Multi-kinase-IN-12
Multi kinase Inhibitor
Multi-kinase-IN-12 is a potent non-selective multi-kinase inhibitor that targets several critical pathways in cancer biology. It demonstrates effective inhibition against human kinases including Flt3 (IC50 < 0.001 μM), c-Src (0.002 μM), and KDR (0.004 μM), among others. This compound is applicable in research focused on solid tumors, providing a valuable tool for elucidating the roles of various kinases in tumor progression and treatment response.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 597544-21-3 |
| Applications | Multi kinase Inhibitor |
| Formula | C23H23N5O2 |
| Molecular Weight | 401.47 |
| SMILES | N=1C=CC(=CC1)C=2C=NN3C=C(C=NC23)C=4C=CC(OCCN5CCOCC5)=CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.