Fig. 1 · Structure
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Multi-kinase-IN-3
Angiokinase Inhibitor
Multi-kinase-IN-3 is a potent inhibitor targeting angiokinases, specifically VEGFR-2 and PDGFRβ. It demonstrates significant inhibitory activity with IC50 values of 58.3 nM and 55 nM, respectively. This compound is valuable for research applications involving angiogenesis and vascular biology, providing insights into tumor growth and progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2091950-43-3 |
| Applications | Angiokinase Inhibitor |
| Formula | C33H33N5O3 |
| Molecular Weight | 547.65 |
| SMILES | O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N4C=CC=C4CN5CCN(C)CC5)C=C3)/C6=CC=CC=C6)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.