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MurB-IN-1

MurB Inhibitor

MurB-IN-1 is a selective inhibitor of uridine diphosphate-N-acetylenolpyruvylglucosamine reductase (MurB), exhibiting a Kd of 3.57 μM. By targeting MurB, this compound is instrumental in research focused on combating Pseudomonas aeruginosa, an opportunistic pathogen associated with serious infections. Its inhibition of MurB disrupts bacterial cell wall biosynthesis, making it a valuable tool in antimicrobial research and the development of novel antibiotic therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2883232-46-8
Applications	MurB Inhibitor
Formula	C₁₂H₇Cl₂F₃N₂O₂
Molecular Weight	339.10
SMILES	CC1=CC(Cl)=C(C=C1N2N=CC(C(O)=O)=C2C(F)(F)F)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.