Mutant IDH1-IN-1

Catalog No.: A21359

mutant-selective IDH1 inhibitor

Mutant IDH1-IN-1

Mutant IDH1-IN-1 Chemical Structure

CAS NO. 1355326-21-4

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

Availability: In stock

Package Price Qty
5 mg
$171.00
10 mg
$295.00
50 mg
$874.00
100 mg
$1,748.00
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Biological Activity

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.28 mL 200.57 mL
0.5 mM 4.01 mL 20.06 mL 40.11 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21359
Actions Inhibitor
M. Wt 498.59
Formula C30H31FN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1355326-21-4
SMILES O=C(C(C1=C(C)C=CC=C1)N(C(CN2C=NC3=C2C=CC=C3)=O)C4=CC(F)=CC=C4)NC5CCCCC5

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