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Biological Activity
Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.76 mL | 108.81 mL | 217.61 mL |
| 0.5 mM | 4.35 mL | 21.76 mL | 43.52 mL |
| 1 mM | 2.18 mL | 10.88 mL | 21.76 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21339 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1429176-69-1 |
| Formula | C24H31F2N5O2 |
| M. Wt | 459.53 |
| Purity | >98% |
| SMILES | O=C1OC[[email protected]](C(C)C)N1C2=NC(N[[email protected]](C3=CC=C(CN4CCC(F)(F)CC4)C=C3)C)=NC=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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