MW073 is a potent and selective antagonist of the 5-HT2B receptor, exhibiting an IC50 of 70 nM. This compound inhibits receptor activity and β-arrestin-1 recruitment in a concentration-dependent manner. MW073 has demonstrated the ability to improve synaptic plasticity and alleviate behavioral deficits, including aggression, in mouse models of Alzheimer’s disease. It is suitable for research applications focused on Alzheimer’s disease and related neurological conditions.
MW073 is a potent and selective antagonist of the 5-HT2B receptor, exhibiting an IC50 of 70 nM. This compound inhibits receptor activity and β-arrestin-1 recruitment in a concentration-dependent manner. MW073 has demonstrated the ability to improve synaptic plasticity and alleviate behavioral deficits, including aggression, in mouse models of Alzheimer’s disease. It is suitable for research applications focused on Alzheimer’s disease and related neurological conditions.
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