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MyD88-IN-2

Myeloid differentiation primary response 88 Inhibitor

MyD88-IN-2 is a selective inhibitor of Myeloid differentiation primary response 88 (MyD88) with an affinity (Kd) of 15 μM. This compound demonstrates protective effects in mouse models of lipopolysaccharide (LPS)-induced and sepsis-induced acute lung injury (ALI). MyD88-IN-2 serves as a valuable tool for studying inflammatory responses and the role of MyD88 signaling in various disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3067479-71-1
Applications	Myeloid differentiation primary response 88 Inhibitor
Formula	C₂₂H₂₆BrN₃O₂
Molecular Weight	444.36
SMILES	O[C@@H](CN1CCN(CC2=CC3=C(C=CC=C3)N2)CC1)COC4=CC=C(Br)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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MyD88-IN-2

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MyD88-IN-2 5 mg