Fig. 1 · Structure
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Myosin modulator 2
Myosin Modulator
Myosin Modulator 2 (Compound B172) is a modulator of myosin that selectively inhibits ATPase activity in rabbit psoas muscle, porcine atria, and porcine ventricles, with IC25 values of 2.013 μM, 2.94 μM, and 20.93 μM, respectively. This compound demonstrates significant regulation of systolic cardiac performance in Sprague Dawley rats, making it a valuable tool in cardiac physiology research and drug development studies focusing on muscle contractility and cardiovascular function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 3034189-87-9 |
| Applications | Myosin Modulator |
| Formula | C18H16FN5O2 |
| Molecular Weight | 353.35 |
| SMILES | O=C1NC2=CC=C(F)C=C2CN1CC(N[C@H](C3=NC=C(C#N)C=C3)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.