Fig. 1 · Structure

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N-19004

FPR1 Antagonist

N-19004 is a potent FPR1 antagonist that exhibits broad-spectrum antibacterial activity against various pathogens. Additionally, it demonstrates significant neuroprotective effects in the rd10 mouse model of retinitis pigmentosa by attenuating retinal dysfunction, mitigating rod and cone degeneration, and reducing immune cell activation and inflammation. N-19004 further promotes edema absorption and reduces the size of laser-induced choroidal lesions through its dual anti-inflammatory and anti-angiogenic properties. This compound is valuable for research into retinal degenerative diseases, particularly retinitis pigmentosa.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2996841-28-0
Applications FPR1 Antagonist
Formula C29H38N8O2S
Molecular Weight 562.73
SMILES
CC(C)(C1=CC(NC(CC/N=C(N)/N)=O)=C(C(NC(CC/N=C(N)/N)=O)=C1)SCC2=CC=C3C=CC=CC3=C2)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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