Fig. 1 · Structure

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N-(3-Hydroxyoctanoyl)-DL-homoserine lactone

LuxR Inhibitor

N-(3-Hydroxyoctanoyl)-DL-homoserine lactone is a competitive inhibitor of the quorum sensing receptor LuxR, exhibiting an IC50 value of 4 μM. This compound selectively targets quorum sensing mechanisms in Gram-negative bacteria, including Pseudomonas aeruginosa. N-(3-Hydroxyoctanoyl)-DL-homoserine lactone is of significant interest for studies involving bacterial infections and the modulation of microbial communication.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 853799-77-6
Applications LuxR Inhibitor
Formula C12H21NO4
Molecular Weight 243.30
SMILES
O=C1C(NC(CC(CCCCC)O)=O)CCO1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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