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N-(9-Fluorenylmethoxycarbonyl) doxorubicin

Doxorubicin Derivative

N-(9-Fluorenylmethoxycarbonyl) doxorubicin is a derivative of doxorubicin, designed to enhance its therapeutic efficacy while minimizing side effects. This compound achieves its biological activity by intercalating into DNA, thereby inhibiting topoisomerase II and preventing DNA replication. It is primarily utilized in research applications focusing on cancer treatment and the investigation of drug resistance mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	136582-53-1
Applications	Doxorubicin Derivative
Formula	C₄₂H₃₉NO₁₃
Molecular Weight	765.76
SMILES	OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(OCC6C7=CC=CC=C7C8=CC=CC=C86)=O)=C1C[C@](O)(C4)C(CO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.