Fig. 1 · Structure
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N-Acetyl lysyltyrosylcysteine amide
Myeloperoxidase Inhibitor
N-Acetyl lysyltyrosylcysteine amide is a reversible and specific inhibitor of myeloperoxidase (MPO), exhibiting non-toxic properties. This tripeptide effectively inhibits the production of toxic oxidants by MPO, contributing to reduced neuronal damage and preservation of brain tissue and neurological function following stroke events. Additionally, it impedes MPO-dependent processes such as hypochlorous acid generation, protein nitration, and oxidation of low-density lipoproteins (LDL), making it a valuable tool in neuroprotection studies and research on oxidative stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1287585-40-3 |
| Applications | Myeloperoxidase Inhibitor |
| Formula | C20H31N5O5S |
| Molecular Weight | 453.56 |
| SMILES | SC[C@@H](C(N)=O)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CCCCN)NC(C)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.