N-Arachidonoyl-L-serine is an endocannabinoid that primarily targets Akt to induce phosphorylation in endothelial cells. It facilitates endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. Additionally, N-Arachidonoyl-L-serine demonstrates neuroprotective effects following traumatic brain injury by reducing apoptosis. It also promotes the opening of KV7.1/KCNE1 channels in mammalian cells, shortening action potential duration in cardiomyocytes. This compound is valuable for research in cardiovascular, cerebrovascular, and neurological disorders.
N-Arachidonoyl-L-serine is an endocannabinoid that primarily targets Akt to induce phosphorylation in endothelial cells. It facilitates endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. Additionally, N-Arachidonoyl-L-serine demonstrates neuroprotective effects following traumatic brain injury by reducing apoptosis. It also promotes the opening of KV7.1/KCNE1 channels in mammalian cells, shortening action potential duration in cardiomyocytes. This compound is valuable for research in cardiovascular, cerebrovascular, and neurological disorders.
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