Fig. 1 · Structure
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N-Biotinyl p-aminophenyl arsenic acid
Bifunctional Reagent
N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent targeting streptavidin and dithiols. It exhibits key biological activity by reducing Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors, with an IC50 range of 10-300 nM. This compound also provides protection to the receptor from irreversible alkylation by bromoacetylcholine, making it valuable for probing receptor interactions and studying cholinergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 212391-23-6 |
| Applications | Bifunctional Reagent |
| Formula | C16H22AsN3O4S |
| Molecular Weight | 427.35 |
| SMILES | O=[AsH](O)C(C=C1)=CC=C1NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.