Fig. 1 · Structure

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N-Boc-N-deshydroxyethyl Dasatinib-d8

Stable Isotope

N-Boc-N-deshydroxyethyl Dasatinib-d8 is a deuterated form of N-Boc-N-deshydroxyethyl Dasatinib, serving as a stable isotope standard. Its primary mechanism involves inhibition of multiple tyrosine kinases, which plays a critical role in cellular signaling pathways associated with cancer. This reagent is beneficial for quantitative studies in pharmacokinetics and metabolism, facilitating research on drug efficacy and dynamics in various biological systems.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1263379-04-9
Applications Stable Isotope
Formula C25H22D8ClN7O3S
Molecular Weight 552.12
SMILES
CC1=NC(NC2=NC=C(C(NC3=C(C=CC=C3Cl)C)=O)S2)=CC(N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C(OC(C)(C)C)=O)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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