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N-Boc-SBP-0636457-OH

Ligands for E3 Ligase

N-Boc-SBP-0636457-OH is a ligand specifically targeting E3 ubiquitin ligases, facilitating the recruitment of IAP E3 ligases. This compound can be conjugated with Bcl-xL ligands via a linker to create the PROTAC Bcl-xL degrader-1, advancing research in targeted protein degradation and therapeutic applications in cancer biology. Its utility in the development of bifunctional molecules positions it as a valuable tool for studying protein homeostasis and signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2450350-79-3
Applications	Ligands for E3 Ligase
Formula	C₃₀H₄₄N₄O₇
Molecular Weight	572.69
SMILES	O=C(N[C@@H]1CCCC2=C1C=CC(O)=C2)[C@@H]3C(C)(C[C@@]([H])(N3C4=O)OCC[C@@H]4NC([C@@H](N(C)C(OC(C)(C)C)=O)C)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.