Fig. 1 · Structure
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N-Boc-Sitagliptin
Dipeptidyl Peptidase
N-Boc-Sitagliptin is an important intermediate in the synthesis of the dipeptidyl peptidase 4 (DPP-4) inhibitor, Sitagliptin. This compound is utilized in the production of therapeutic agents aimed at managing type 2 diabetes by enhancing insulin secretion and lowering glucose levels. Its role in DPP-4 inhibition makes it a valuable reagent for research applications related to metabolic disorders and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 486460-23-5 |
| Applications | Dipeptidyl Peptidase |
| Formula | C21H23F6N5O3 |
| Molecular Weight | 507.43 |
| SMILES | FC(F)(C1=NN=C2N1CCN(C(C[C@H](NC(OC(C)(C)C)=O)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.