Fig. 1 · Structure
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N-Butyl-N-(4-hydroxybutyl)nitrosamine
Bladder Cancer Inducer
N-Butyl-N-(4-hydroxybutyl)nitrosamine is a potent mutagen that primarily targets the urothelial cells of the urinary bladder, leading to significant mutagenesis. This compound is commonly employed in research to induce bladder cancer in rodent models, facilitating studies on carcinogenesis and cancer development. Its use is critical for understanding the mechanisms of bladder cancer and evaluating potential chemopreventive interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 3817-11-6 |
| Applications | Bladder Cancer Inducer |
| Formula | C8H18N2O2 |
| Molecular Weight | 174.24 |
| Synonyms | BBN |
| SMILES | CCCCN(N=O)CCCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.