Fig. 1 · Structure
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N-Cbz-hydroxy-L-proline
Amino Acid Derivative
N-Cbz-hydroxy-L-proline is a chiral amino acid derivative featuring a carbobenzyloxy (Cbz) protection. This compound is primarily utilized in the synthesis of polypeptides and pharmaceutical intermediates, facilitating efficient coupling and modification processes. It can undergo decarboxylation when exposed to AlCl3/HFIP conditions, making it a valuable building block in organic synthesis and medicinal chemistry.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 13504-85-3 |
| Applications | Amino Acid Derivative |
| Formula | C13H15NO5 |
| Molecular Weight | 265.26 |
| SMILES | O=C(O)[C@H]1N(C(OCC2=CC=CC=C2)=O)C[C@H](O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.