Fig. 1 · Structure
Documents & Downloads
N-CBZ-Phe-Arg-AMC
Cat. No.
A39807
CAS
65147-22-0
Cathepsin Substrate
N-CBZ-Phe-Arg-AMC is a specific substrate for lysosomal cathepsin enzymes, primarily utilized for assessing cathepsin activity. This compound exhibits fluorescent properties upon substrate cleavage, making it suitable for monitoring lysosomal protease activity in various biological samples. Its applications extend to studies on proteolytic processing and the role of cathepsins in cellular functions and disease states.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 65147-22-0 |
| Applications | Cathepsin Substrate |
| Formula | C33H36N6O6 |
| Molecular Weight | 612.68 |
| Synonyms | Z-FR-AMC |
| SMILES | CC=1C=2C(=CC(NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC(OCC4=CC=CC=C4)=O)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.