Fig. 1 · Structure
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N-Desethyl Brinzolamide oxalate
Carbonic anhydrase Inhibitor
N-Desethyl Brinzolamide oxalate is a potent inhibitor of carbonic anhydrase II and carbonic anhydrase IV, demonstrating IC50 values of 1.28 nM and 128 nM, respectively. This compound is valuable for research involving the regulation of bicarbonate and pH balance in physiological systems. It is commonly utilized in studies related to glaucoma treatment and other conditions influenced by carbonic anhydrase activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2775292-24-3 |
| Applications | Carbonic anhydrase Inhibitor |
| Formula | C12H19N3O9S3 |
| Molecular Weight | 445.49 |
| Synonyms | AL-8520 oxalate |
| SMILES | O=[S](C(S1)=C([C@H](C2)N)C=C1[S](N)(=O)=O)(N2CCCOC)=O.OC(C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.