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N-Deshydroxyethyl Dasatinib-C3-NH2

Target Protein Ligand-Linker Conjugate

N-Deshydroxyethyl Dasatinib-C3-NH2 is a targeted protein ligand-linker conjugate designed for selective interaction with LCK. This compound incorporates a specific ligand and a PROTAC linker, facilitating the recruitment of E3 ligases to promote targeted protein degradation. N-Deshydroxyethyl Dasatinib-C3-NH2 serves as a crucial component in the synthesis of the PROTAC SJ11646, making it valuable for researchers studying protein homeostasis and degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1430089-58-9
Applications	Target Protein Ligand-Linker Conjugate
Formula	C₂₃H₂₉ClN₈OS
Molecular Weight	501.05
Synonyms	N-Deshydroxyethyl BMS-354825-C3-NH2
SMILES	O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCCN)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.