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N-Desmethyl clindamycin hydrochloride

Clindamycin Metabolite

N-Desmethyl clindamycin hydrochloride is a metabolite of Clindamycin, primarily targeting bacterial ribosomal RNA to inhibit protein synthesis. This compound exhibits significant cytotoxic effects on various cancer cell lines, including L1210, KB, RPMI 6410, and RPMI 1788, with LD50 values ranging from 0.07 to 0.32 μM. N-Desmethyl clindamycin hydrochloride is applicable in research focused on infectious diseases and cancer therapeutics, particularly in understanding mechanisms of action and cytotoxicity profiles.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	25532-03-0
Applications	Clindamycin Metabolite
Formula	C₁₇H₃₂Cl₂N₂O₅S
Molecular Weight	447.42
SMILES	O=C([C@@H]1C[C@H](CN1)CCC)N[C@@H]([C@]2([H])[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](Cl)C.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.