Fig. 1 · Structure

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N-Desmethyl clotiazepam

Active Metabolite of Clotiazepam

N-Desmethyl clotiazepam is an active metabolite of Clotiazepam, primarily functioning as a positive allosteric modulator of the GABA-A receptor. It exhibits anxiolytic and sedative properties, making it valuable for research in neuropharmacology. This compound is utilized in studies investigating the mechanisms of action of benzodiazepines and their effects on anxiety and sleep disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 33671-37-3
Applications Active Metabolite of Clotiazepam
Formula C15H13ClN2OS
Molecular Weight 304.79
Synonyms Desmethylclotiazepam
SMILES
CCC1=CC2=C(S1)NC(CN=C2C3=C(C=CC=C3)Cl)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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