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N-Desmethyl topotecan

Topotecan Metabolite

N-Desmethyl topotecan, a primary metabolite of topotecan, serves as a valuable tool in pharmacokinetic studies. This compound can be detected in biological matrices such as plasma, urine, and feces, facilitating the investigation of topotecan's metabolic pathways and therapeutic efficacy. It is primarily used in cancer research, particularly in studies evaluating the drug's pharmacological effects and overall safety profile.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	190710-79-3
Applications	Topotecan Metabolite
Formula	C₂₂H₂₁N₃O₅
Molecular Weight	407.42
SMILES	CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5CNC)=NC4=CC=C5O)=C2)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.