Fig. 1 · Structure

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N-Despropyl Ropinirole

D2/D3 Receptor Agonist

N-Despropyl Ropinirole (SKF-104557) is a potent agonist targeting dopamine D2 and D3 receptors. As an active metabolite of Ropinirole, it exhibits full agonistic activity at human D2 and D3 receptors while acting as a partial agonist at the hD4 receptor. This compound is valuable for research applications investigating dopaminergic signaling and potential therapeutic strategies for diseases such as Parkinson's and schizophrenia.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 106916-16-9
Applications D2/D3 Receptor Agonist
Formula C13H18N2O
Molecular Weight 218.29
Synonyms SKF-104557
SMILES
CCCNCCC1=C2CC(NC2=CC=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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