Fig. 1 · Structure

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N-dodecanoyl-L-Homoserine lactone

QS Signaling Molecule

N-dodecanoyl-L-Homoserine lactone (C12-HSL) acts as a quorum sensing (QS) signaling molecule involved in bacterial communication. Its inhibition of QS pathways has been shown to disrupt biofilm formation in Pseudomonas aeruginosa, making it a valuable tool for studying bacterial behavior and biofilm dynamics. This compound can be utilized in research focused on microbial ecology, pathogenesis, and the development of anti-biofilm strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 137173-46-7
Applications QS Signaling Molecule
Formula C16H29NO3
Molecular Weight 283.41
Synonyms C12-HSL
SMILES
CCCCCCCCCCCC(N[C@H]1CCOC1=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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