Fig. 1 · Structure
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N-Ethyl-N-nitrosourea
DNA Alkylating Agent
N-Ethyl-N-nitrosourea (ENU) is a potent DNA alkylating agent known for its ability to induce mutations by alkylating nucleobases. Its mechanism leads to disruption of DNA structure, resulting in bone marrow suppression and the generation of leukemic cells. Additionally, ENU exhibits teratogenic effects, influencing tumor formation and causing morphological abnormalities in developing embryos. This compound is widely used in research related to carcinogenesis, genetic disorders, and the study of central nervous system tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 759-73-9 |
| Applications | DNA Alkylating Agent |
| Formula | C3H7N3O2 |
| Molecular Weight | 117.11 |
| Synonyms | ENU; N-Nitroso-N-ethylurea |
| SMILES | O=NN(CC)C(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.