Fig. 1 · Structure
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N-Formyl-L-histidine
Histidine Derivative
N-Formyl-L-histidine is a histidine derivative that exhibits binding affinity to histidyl-tRNA synthetase, demonstrated by a Ki value of 4.6 μM. This compound acts as a competitive inhibitor of L-histidine ammonia-lyase and significantly inhibits the formation of urocanic acid from L-histidine, with a Ki value of 4.26 mM. Its properties make it suitable for studies involving amino acid metabolism and enzyme regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 15191-21-6 |
| Applications | Histidine Derivative |
| Formula | C7H9N3O3 |
| Molecular Weight | 183.16 |
| Synonyms | Formyl-L-histidine |
| SMILES | [C@H](CC1=CN=CN1)(C(O)=O)NC=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.