Fig. 1 · Structure
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N-Hydroxymethyl succinimide
Promoiety
N-Hydroxymethyl succinimide serves as a promoiety, primarily functioning as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs). By enhancing the lipophilicity of NSAIDs, it effectively reduces gastrointestinal toxicity associated with these compounds. This reagent shows significant potential in the development of advanced anti-inflammatory drug delivery systems, making it valuable for research applications in medicinal chemistry and pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5146-68-9 |
| Applications | Promoiety |
| Formula | C5H7NO3 |
| Molecular Weight | 129.11 |
| Synonyms | N-Methylolsuccinimide |
| SMILES | C1CC(=O)N(CO)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.