Fig. 1 · Structure
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N-Hydroxymethylsorafenib
Sorafenib Metabolite
N-Hydroxymethylsorafenib is a metabolite of Sorafenib, primarily targeting multiple kinases involved in cell proliferation and apoptosis. This compound is significant for studies focusing on the metabolic pathways of Sorafenib and its biological effects. Research involving N-Hydroxymethylsorafenib may provide insights into its pharmacokinetics and potential therapeutic implications in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1380310-94-0 |
| Applications | Sorafenib Metabolite |
| Formula | C21H16ClF3N4O4 |
| Molecular Weight | 480.82 |
| SMILES | O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.