(-)-N-methylcoclaurine ((–)-(1R)-N-methylcoclaurine)

Catalog No.: A97315
Alkaloid
(-)-N-methylcoclaurine is a benzylisoquinoline alkaloid that functions as a melanogenesis inhibitor, exhibiting an IC50 of 6.5 μM. This compound effectively inhibits theophylline-stimulated melanogenesis in melanoma cells, making it a valuable tool for studying skin hyperpigmentation disorders. Its unique properties enable research into potential therapeutic strategies for conditions related to excessive melanin production.
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Size Price Stock Qty
1mg
$605.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description(-)-N-methylcoclaurine is a benzylisoquinoline alkaloid that functions as a melanogenesis inhibitor, exhibiting an IC50 of 6.5 μM. This compound effectively inhibits theophylline-stimulated melanogenesis in melanoma cells, making it a valuable tool for studying skin hyperpigmentation disorders. Its unique properties enable research into potential therapeutic strategies for conditions related to excessive melanin production.
Product Information
Catalog NumA97315
FormulaC18H21NO3
Molecular Weight299.36
CAS Number5096-70-8
SMILESOC1=CC2=C(C=C1OC)CCN(C)[C@@H]2CC3=CC=C(O)C=C3
Synonyms(–)-(1R)-N-methylcoclaurine
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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