Fig. 1 · Structure
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N,N'-Methylenebisacrylamide
Crosslinker
N,N'-Methylenebisacrylamide is a crosslinking agent predominantly utilized in the synthesis of polyacrylamide gels. This compound facilitates the formation of a stable three-dimensional network, which is critical for various applications in electrophoresis and chromatography. Research indicates that N,N'-Methylenebisacrylamide can modulate biochemical pathways by increasing CYP2E1 and P53 expression, and promoting apoptosis through the activation of cleaved caspase-3. Additionally, it has been associated with alterations in reproductive health and potential hepatic toxicity, making it valuable in studies investigating cellular damage and carcinogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 110-26-9 |
| Applications | Crosslinker |
| Formula | C7H10N2O2 |
| Molecular Weight | 154.17 |
| Synonyms | Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide |
| SMILES | C=CC(NCNC(C=C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.