Fig. 1 · Structure

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N-Nitroso-tris-chloroethylurea

Induced tumor model

N-Nitroso-tris-chloroethylurea (NTCU) is a chemical agent primarily used for inducing lung squamous cell carcinoma in various mouse strains. It effectively promotes tumor formation in SWR/J, NIH Swiss, A/J, BALB/cJ, and FVB/J mice when applied topically, offering a valuable model for cancer research. This reagent can facilitate studies on tumor biology, therapeutic interventions, and the mechanisms of carcinogenesis.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 69113-01-5
Applications Induced tumor model
Formula C7H12Cl3N3O2
Molecular Weight 276.55
SMILES
O=NN(CCCl)C(N(CCCl)CCCl)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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