Fig. 1 · Structure
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N-Nitrosodiethylamine-d4
Stable Isotope
N-Nitrosodiethylamine-d4 is a deuterated form of the potent hepatocarcinogen N-Nitrosodiethylamine (DEN), which functions as a dialkylnitrosoamine. This compound is primarily found in various sources, including tobacco smoke, certain foods, and alcoholic beverages, and is known to induce significant alterations in nuclear enzymes related to DNA repair and replication. Research demonstrates that N-Nitrosodiethylamine can lead to tumor formation across multiple animal species, particularly affecting the nasal cavity, trachea, lungs, esophagus, and liver. This stable isotope is valuable for studies involving metabolic pathways and the mechanisms of carcinogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1346603-41-5 |
| Applications | Stable Isotope |
| Formula | C4H6D4N2O |
| Molecular Weight | 106.16 |
| Synonyms | Diethylnitrosamine-d4; DEN-d4; DENA-d4 |
| SMILES | CC([2H])([2H])N(N=O)C([2H])([2H])C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.