Fig. 1 · Structure

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N,O-Didesmethylvenlafaxine

Venlafaxine Metabolite

N,O-Didesmethylvenlafaxine is a key metabolite of venlafaxine, functioning primarily as a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor. This compound exhibits significant biological activity in modulating serotonin and norepinephrine levels, making it relevant in studies on mood disorders and antidepressant pharmacology. It serves as an important analytical standard for understanding the pharmacokinetics and pharmacodynamics of venlafaxine and its effects in clinical research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 135308-74-6
Applications Venlafaxine Metabolite
Formula C15H23NO2
Molecular Weight 249.35
Synonyms NODVFX
SMILES
OC1=CC=C(C(C2(O)CCCCC2)CNC)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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