Fig. 1 · Structure
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N,S-Bis-Fmoc-Glutathione
Glyoxalase II Inhibitor
N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a Ki value of 0.75 μM and an IC50 of 2.5 μM. This compound is highly valuable for research involving glycation processes, oxidative stress, and related pathways. Its ability to modulate glyoxalase II activity makes it a useful tool for investigating cellular responses to reactive carbonyl species and their implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 149438-56-2 |
| Applications | Glyoxalase II Inhibitor |
| Formula | C40H37N3O10S |
| Molecular Weight | 751.80 |
| SMILES | C(OC(N[C@@H](CCC(N[C@@H](CSC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(NCC(O)=O)=O)=O)C(O)=O)=O)C4C=5C(C=6C4=CC=CC6)=CC=CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.