Fig. 1 · Structure

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N-tert-Butyl-α-phenylnitrone-d14

Stable Isotope

N-tert-Butyl-α-phenylnitrone-d14 is a deuterium-labeled variant of N-tert-Butyl-α-phenylnitrone, a nitrone compound recognized for its free radical scavenging capabilities. This reagent effectively forms nitroxide spin adducts and demonstrates inhibition of COX2 catalytic activity. Key biological activities include potent reactive oxygen species (ROS) scavenging, alongside anti-inflammatory, neuroprotective, anti-aging, and anti-diabetic properties. Additionally, it has the ability to penetrate the blood-brain barrier, making it valuable for various research applications in the fields of oxidative stress and neurobiology.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 119391-92-3
Applications Stable Isotope
Formula C11HD14NO
Molecular Weight 191.33
SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])/N(=C/C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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