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N1-Methyl-GTP

GTP Analog

N1-Methyl-GTP is a nucleotide analog of GTP that primarily targets RNA triphosphatase. Exhibiting a half-maximal inhibitory concentration of 8.1 μM and an inhibition constant of 1.5 μM against yeast RTPase, it serves as an effective probe for investigating the structural dynamics of the active site. This compound is valuable for research into the mechanisms of substrate recognition and the functional properties of RNA triphosphatases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	52940-67-7
Applications	GTP Analog
Formula	C₁₁H₁₈N₅O₁₄P₃
Molecular Weight	537.21
SMILES	O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.