Fig. 1 · Structure
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N1-Methylpseudouridine-5′-triphosphate solution (100mM)
Nucleobase-modified Nucleotide
N1-Methylpseudouridine-5′-triphosphate is a nucleobase-modified nucleotide that enhances mRNA synthesis by providing reduced immunogenicity and improved stability compared to unmodified counterparts. This compound is essential for researchers focused on developing mRNA therapeutics and vaccines, as it contributes to the generation of more stable and effective mRNA molecules in various applications, including gene expression studies and RNA-based drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1428903-59-6 |
| Applications | Nucleobase-modified Nucleotide |
| Formula | C10H17N2O15P3 |
| Molecular Weight | 498.17 |
| Synonyms | 1-Methylpseudouridine-5′-triphosphate |
| SMILES | O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.