Fig. 1 · Structure

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N3-L-Cit-OH

Click Chemistry Reagent

N3-L-Cit-OH is a click chemistry reagent featuring an azide functional group. It is designed for the construction of peptidomimetic antibody-drug conjugates (ADCs) through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing substrates. Additionally, N3-L-Cit-OH can participate in ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups, making it a versatile tool for bioconjugation applications in chemical biology and drug development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1799421-66-1
Applications Click Chemistry Reagent
Formula C6H11N5O3
Molecular Weight 201.18
SMILES
NC(NCCC[C@@H](C(O)=O)N=[N+]=[N-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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