Fig. 1 · Structure

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N6,2′-O-Dimethyladenosine

FTO Substrate

N6,2'-O-Dimethyladenosine serves as a substrate for the fat mass and obesity-associated gene (FTO), playing a critical role in mRNA cap modification. This compound is involved in the dynamic regulation of mRNA stability, translation efficiency, and subsequent protein expression. Its unique properties make it a valuable tool for research into obesity and related metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 57817-83-1
Applications FTO Substrate
Formula C12H17N5O4
Molecular Weight 295.29
SMILES
O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3NC)=C3N=C2)O[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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