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N7-Methyl-guanosine-5'-triphosphate-5'-adenosine

Cap analog

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) serves as a dinucleotide cap analog, primarily targeting RNA synthesis and stability. This compound is essential for in vitro RNA transcription, mimicking the natural cap structure of eukaryotic mRNAs, thereby enhancing the stability and translational efficiency of RNA transcripts. Ideal for use in studies related to gene expression and RNA processing.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	62828-63-1
Applications	Cap analog
Formula	C₂₁H₂₉N₁₀O₁₇P₃
Molecular Weight	786.43
Synonyms	m7GpppA
SMILES	O=P(O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC(C2=NC=N3)=C3N)O1)OP(OP(OC[C@H]4O[C@@H](N5C(N=C(N6)N)=C([N+](C)=C5)C6=O)[C@H](O)[C@@H]4O)([O-])=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.