Fig. 1 · Structure
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nAChR agonist 2
α4β2 nAChR Agonist
nAChR agonist 2 is a selective agonist for the α4β2 nicotinic acetylcholine receptor (nAChR) with a dissociation constant (Kd) of 26 nM. This compound demonstrates significant biological activity in modulating neurotransmitter release and enhancing synaptic transmission. It is valuable for research applications involving neuropharmacology and the study of neurological disorders associated with cholinergic signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 252870-46-5 |
| Applications | α4β2 nAChR Agonist |
| Formula | C11H16N2 |
| Molecular Weight | 176.26 |
| SMILES | C[C@H](NC)C/C=C/C1=CC=CN=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.